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1 article(s) from Monney, Baptiste

Synthesis of structurally diverse 3,4-dihydropyrimidin-2(1H)-ones via sequential Biginelli and Passerini reactions

Andreas C. Boukis,
Baptiste Monney and
Michael A. R. Meier

Beilstein J. Org. Chem. 2017, 13, 54–62, doi:10.3762/bjoc.13.7

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Graphical Abstract

Scheme 1: a) Proposed mechanism of the Biginelli reaction according to [6]. b) Proposed mechanism of the Passeri...

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Figure 1: Bifunctional components for the Biginelli–Passerini tandem reaction.

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Figure 2: Stacked ¹H NMR spectra and signal assignment. Top: DHMP acid 17; bottom: Biginelli–Passerini tandem...

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Figure 3: Representative HSQC spectrum of the pure Biginelli–Passerini tandem product 21, expansions and sign...

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Figure 4: Stereoisomers formed in the Biginelli–Passerini tandem reaction. The homo (RR, SS) and hetero pairs...

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Published 09 Jan 2017

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